ENDOCRIN STATUS IN HEALTHY SUKLING PIGLETS AND DIARRHOEA PIGLETS IN THE FIRST DAYS OF LIFE PUBLISHED

Olga Alina RADA, H. CERNESCU, H. SĂRĂNDAN, Florina RADU, Mihaela FERICEAN
The experiment was carried out with 27 piglets from birth to the age of three days, of which 11healthy piglets and 16 piglets with diarrhoea. All piglets were weighed. In piglets with diarrhoea, theblood was collected in the day when the diarrhoea started. After the serum was examined, it wasseparated and preserved by freezing up to the moment of hormone dosage. The cortisol and insulinconcentration was measured with a HPLC. The glycaemia was measured with an Accucek device. Thedata obtained were processed statistically through a non-parametric test, the Mann Whitney U Test. Bodyweight measurements in piglets suffering from diarrhoea and healthy piglets showed that diarrhoeapiglets display a lower average body weight starting with the first day of diarrhoea, thus the difference inbody weight can not be accounted to dehydration. Glycaemia in piglets with diarrhoea is, starting withthe first day of diarrhoea, significantly lower (p<0.05) than healthy piglet glycaemia; similarly, the levelof serum insulin (p<0.05) as well as that of serum cortisol (p<0.001) are lower in diarrhoea piglets.What is more, the serum level of the insulin does not correlate significantly with glycaemia (r=0.27;p>0.05), from a statistic point of view. The serum cortisol does not correlate significantly in healthypiglets (r=0.071; p>0.05), statistically, and also not in diarrhoea piglets (r=0.46; p>0.05). On thecontrary, there is a strong correlation of the serum insulin with the serum cortisol in healthy piglets(r=0.86; p<0.001) as well as in diarrhoea ones (r=0.92; p=0.0000). The reduction of the serum cortisollevel in diarrhoea piglets can represent a facilitating factor in the diarrhoea pathogenesis, or it can bethe consequence of subnutrition and diarrhoea.
The experiment was carried out with 27 piglets from birth to the age of three days, of which 11 healthy piglets and 16 piglets with diarrhoea. All piglets were weighed. In piglets with diarrhoea, the blood was collected in the day when the diarrhoea start
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