MORPHOLOGICAL AND CHEMICAL CHANGES IN BLOOD CELLS IN ACUTE LEUKAEMIA IN HUMANS NOTE 2. MORPHOLOGICAL CHANGES OF FIGURATIVE ELEMENTS BLOOD AND BONE MARROW IN PATIENTS WITH ACUTE LEUKAEMIA SUSPICION PUBLISHEDOlga – Alina RADA, Diana Brezovan, Corina Luminiţa MĂRAN, Mihaela OSTAN email@example.com
Capturing and highlighting morphological changes that occur in the examination of a peripheral blood smear or bone marrow are important in the diagnosis of acute leukaemia, motivating the goal of this paper. The examination of blood smears from all patients included in the study revealed the presence of blast cells (2-97% of total leukocyte cell line). Of total studied smears, most presented type I and II blasts, which pointed to acute myeloid leukaemia (LAM) 2, 3, 4 and 5; lymphoblastic modest presence pointed to acute lymphoblastic leukaemia (LAL) (4%). About 36% of smears of blood blast cells analyzed showed a pronounced polymorphism, which could not be classified even after performing bone marrow aspirate, requiring further investigation to establish the diagnosis.
blood smear, bone marrow smear, acute leukaemia, blast cells
Biology applied in Agriculture