MORPHOLOGICAL CHANGES OF ERYTHROCYTES IN HYPOCHROMIC ANAEMIA, IN HUMANS PUBLISHEDOlga-Alina Rada, Diana Brezovan, Mihaela Ostan None firstname.lastname@example.org
Hypochromic anaemia cases are characterised by a deficit in synthetizing and then depositing of haemoglobin in erythroblasts and may result from metabolism disorders or poor synthetizing of any haemoglobin component (iron, protoporphyrin, globin). The microscopic exam of peripheral blood smears correlated with the study of automated complete blood cell counts (CBC) leads to the establishment of an efficient treatment which should correct the occurring deficit. The peripheral blood smears were examined under the microscope, establishing erythrocyte size, aspect and haemoglobin load. We observed shape variations (dacrocytes, ovalocytes, stomatocytes) in variable proportions (12.5-43.75%) as well as erythrocyte diameter variations (anisocytosis) associated with hypochromia. The study of automated complete blood cell counts supported the microscopic observations; the erythrocyte number was 38.5% lower, and the haemoglobin quantity and haematocrit value were 26.84%, respectively 23.75% lower than the minimum values of the reference biological interval.
hypochromic anaemia, haemoglobin, blood smear, complete blood cell count (CBC)