Toxicity assesment of chemical compounds that can end up into the environment is extremely important as chemicals have the ability to enter in biological organisms via different pathways and therefore reshape organisms' development. In vitro tests are successfully used to test chemical compounds, but do not provide an overall insight into the toxic potential they may have once reach a whole organism. Study models validated by repeated research, such as Drosophila melanogaster, are used to perform in vivo tests. One of the most significant parameters for testing the toxicity of compounds on the fruit fly is viability. An effective method to study viability in relation to various exogenous substances is by altering the diet of the test organisms. The main aim of the study is to better understand the impact that some chemicals have on animal organisms and to observe the response of fruit fly to different classes of compounds as seen from the viability perspective. Thus, in order to investigate the effects of chemicals we have altered the culture media by adding either natural compounds (different types of water, phytoestrogens) or synthetic compounds (nanoparticles, pesticides). Our findings suggest that the different types of water do not affect the viability of fuit flies and this has also been proven for nanoparticles. Regarding pesticides and phytoestrogens, there is a decrease in viability percentages in a dose-dependent manner.

Drosophila melanogaster, natural compounds, synthetic compounds, viability

biology

Presentation: poster